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Capacity: 200L
Total volume 268L
Working volume: 200L
Dimension: Approx. 200Wx150Dx330H cm, Open distance of headplate lift : 40 cm
Vessel and jacket maximum working pressure: 3 bar (43.5 psig) / 3 bar (43.5 psig)
Type: Double layered fully enclosed capsule-type tank, with an outer temperature protective layer
Material: Direct contact to medium - 316L stainless steel; all others - 304 stainless steel
Surface finish:
Interior polish ≦ 25 Ra/in (0.6 μm) Mechanical polishing; Electropolish optional
Exterior polish ≦ 32 Ra/in (0.8 μm) Mechanical polishing; Electropolish optional
Ports: Ports designed according to user requirements
Piping and valve materials:
Parts that directly contact with the product/medium uses 316L stainless steel (≤25 Ra/in) internal polished tubing (BPE standard) :
A. Internal EP polished diaphragm type pneumatic valve and manual valve (BPE standard)
B. Tubing all welded with orbital welding
C. Vessel bottom drain uses a diaphragm valve, to minimize dead volume
D. Piping designed for ease of transfer to scale up (can be used as a seed fermentation system) or downstream process
Parts that do not directly contact product/medium
A. Constructed with 304 stainless steel
Controller: 12” color industrial touch screen
* User-friendly, graphical control interface
* Includes secure user accounts, with different levels of access
* Use stainless-steel controller cabinet (100 L and above only)
* Modularized and standardized design (Module Skid):
ergonomically designed according to height, ease of vessel clean up, and ease of extraction in relation to vessel bottom valve
* Includes maintenance page with system diagnostics
* All programmed setting values are automatically stored into the built-in memory; the settings will not be lost in case of power outage/interruption.
When power is restored, the interrupted process will automatically resumed
Setting
* Automated sterilization process
* Automated fermentation program
DO
* 0-200%, Control range: 0-100%, adjustable
* Software electrode calibration, with automatic temperature compensation function
* Includes one set of side-inserted stainless steel autoclavable DO electrode
* DO Stat features with intelligent feeding
pH
* PID control with adjustable deadband
* Control range 0 to 14 (2-12 for maximum precision), resolution: 0.01 pH
* Calibration function with automatic temperature compensation function
* Includes one set of side-inserted, autoclavable pH probe with stainless steel housing
* pH Stat features with intelligent feeding
Pump
* Built-in peristaltic pumps
* Each feeding pump can run adjustable 15-step program
* Each pump can be adjusted for speed, forward and backward direction, and manual or automatic mode
* Each of the four peristaltic pumps can be designated for different functions: acid pump, base pump, antifoam pump, or substrate feeding pump
* Optional fifth and six peristaltic pump available
Temperature
* Vessel temperature is measured with a side-inserted PT-100 temperature probe and maintained using PID control.
* Control range: 0-130°C, ±0.1°C. Operational range up to 0-60°C.
Agitation
* Manual or automatic control of agitation speed
* 15-step program to change speed, or use DO cascade control
Air supply and exhaust
Gas supply and dehumidifer: uses in-house air compressor or air dehumidifier
* Includes re-useable, autoclavable 0.2μm air filter for gas inlet
* Gas Inlet (air) Includes mass flow controller: 2 vvm maximum according to the vessel capacity
* Gas Inlet (oxygen) Includes pure oxygen rotameter (manual flow control): 1 vvm maximum according to the vessel capacity
* Includes oxygen gas solenoid valve, with automatic pulsed time control
Air outlet / Exhaust
* Exhaust port with stainless steel condenser
* Includes re-useable, autoclavable 0.2μm air filter
* Includes automated adjustable gas outlet valve to adjust vessel back pressure
* Can control manually or automatically via software
Utility Requirement
Capacity: 200L
Power: Three phase 220V or 380V (note: can be customized to local standard)
Air:
At least 6 bar
400 L/min flow rate
Dehumidified
Oil-free
Peripheral factory water supply:
Cooling water (tap water, at least 15oC below working temperature, must be soft water);
Pressure at least 2 bar
Process water: RO Water
Plant steam: ≥ 2 bar; dry steam with no entrained condensate
Process steam: ≥ 2 bar; dry steam with no entrained condensate
Drain: In situ drain; ≥ 2"
* Customization on the SIP Fermentation system available upon request.
Winpact offers pilot and production scale bioreactor/fermentation systems for all of your large scale fermentation needs. Our standard SIP Production Scale Fermentation System is constructed with BPE standard piping with orbital welding and top grade automatic valves to allow stable and repeatable result for every experiment. All of our features are designed to provide a high level of productivity and automation while maintaining a low operation cost. All other great features including total sterilization process, mechanical seal break indication, golden vessel ratio design and complete selection of optional devices for optimizing the fermentation process.
A. Harvest valve sanitary level diaphragm valve
B. Detachable aseptic feeding device
C. Mechanical seal lubricate and automatic cooling device
D. Pump
E.
- Pneumatic valves for accurate and automatic control
- Orbital welding provides top quality
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